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Collagen-binding Activity (CBA) Profile
Test Code:
500360
Performing Lab: LABCORP ESOTERIX COAGULATION LAB
CPT Code:
85246  83520   
Specimen Container Blue-top (sodium citrate) tube
Specimen Type Plasma, FROZEN
Volume 2.0 mL
Temperature FREEZE Stability: Refrigerate up to 4 hours Acceptable freeze/thaw up to 4 cycles
Specimen Handling CITRATED PLASMA SAMPLES SHOULD BE COLLECTED BY DOUBLE CENTRIFUGATION. Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate.[1] Evacuated collection tubes must be filled to completion to ensure a proper blood to anticoagulant ratio.[2,3] The sample should be mixed immediately by gentle inversion at least six times to ensure adequate mixing of the anti- coagulant with the blood. A discard tube is not required prior to collection of coagulation samples except when using a winged blood collection device (i.e. 'butterfly'), in which case a discard tube should be used.[4,5] When noncitrate tubes are collected for other tests, collect sterile and nonadditive (red-top) tubes prior to citrate (blue-top) tubes. Any tube containing an alternate anticoagulant should be collected after the blue- top tube. Gel-barrier tubes and serum tubes with clot initiators should also be collected after the citrate tubes. Centrifuge for 10 minutes and carefully remove 2/3 of the plasma using a plastic transfer pipette, being careful not to disturb the cells. Deliver to a plastic transport tube, cap, and recentifuge for 10 minutes. Use a second plastic pipette to remove plasma, staying clear of the platelets at the bottom of the tube. Transfer the plasma into a LabCorp PP transpak frozen purple tube with screw cap (LabCorp 49482). FREEZE immediately and maintain frozen until tested. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested. Please print and use the Volume Guide for Coagulation Testing to ensure proper draw volume.
Methodology Enzyme-linked immunosorbent assay (ELISA)
Unacceptable Conditions Lipemia; icteric specimen; hemolysis; clotted specimen; specimen contaminated with heparin (ie, drawn with blood gases)
Days Set-Up M
Shift Performed 1
TAT From Set-Up 3 - 9 Days
Result Code Result Name LOINC
500357 von Willebrand Factor Antigen 27816-8
500359 vWF Collagen Binding 50378-9
500552 vWF Collagen Binding Act. ** 50377-1