CDOS

Myelin Basic Protein (MBP), Cerebrospinal Fluid

Test Code: 123377

Performing Lab: LabCorp

CPT Code: 83873 001

Synonym

MBP

Specimen Type

Cerebrospinal fluid (CSF)

Specimen Container

Plastic transport tube

Volume

1 mL

Minimum Volume

0.8 mL; when oligoclonal banding is ordered along with myelin basic protein, the minimum volume of CSF is 0.9 mL.

Specimen Handling

Centrifuge CSF at 1500xg for 20 minutes and place the supernatant in a separate tube. Ensure that residual fibrin and cellular matter have been removed prior to transport.

Patient Prep

Lumbar puncture should be performed within five days of onset of neurologic symptoms suggestive of multiple sclerosis.

Unacceptable Conditions

Lipemic, hemolyzed, or icteric specimen; CSF should be free from contamination with blood. Hemolysis is associated with falsely-elevated levels of MBP.

Temperature

Room temperature

Methodology

Enzyme-linked immunosorbent assay (ELISA)

Stability

Room Temperature: 14 days
Refrigerated: 14 days
Frozen: 14 days

Result Code	Result Name	LOINC
123378	Myelin Basic Protein, CSF	2638-5

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